S7 Nitrofurantoin Lung Toxicity - Are Steroids Useful?

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Severe nitrofurantoin lung disease resolving without the use of steroids.

We report a case of an elderly woman who developed a severe, chronic pulmonary reaction to nitrofurantoin therapy that she had taken continuously for three years to prevent urinary tract infections. The patient was taking no other drug known to cause lung disease but the diagnosis was delayed by failure to recognize the association between nitrofurantoin and adverse drug reactions affecting the...

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Nitrofurantoin‐induced acute pulmonary toxicity

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Fatal nitrofurantoin lung.

Nitrofurantoin is a drug commonly used for urinary tract infections. It acts by damaging bacterial DNA. It is given in dose of 50-100 mg orally and is generally considered a safe drug but has occasionally been known to cause pulmonary toxicity which is usually reversible and only rarely fatal. We present a case of an elderly lady receiving nitrofurantoin for her urinary tract infection who deve...

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ژورنال

عنوان ژورنال: Thorax

سال: 2014

ISSN: 0040-6376

DOI: 10.1136/thoraxjnl-2014-206260.13